Hey, Dr. Fauci: Here’s a randomized control study for you…

Its conclusion: Hydroxychloroquine helps patients!
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As reported in the New York Times

Based on a randomized control study, Chinese researchers report that:

  • Coughing and fever eased a day or so earlier in the patients who received hydroxychloroquine, and
  • Based on CT scans, pneumonia improved significantly in 80.6% who received hydroxychloroquine, as opposed to 54.8% in the control group.
  • Only 2 patients had minor side effects from hydroxychloroquine: One had a rash and another had a headache.
  • The illness turned severe in four patients — all in the control group.

According to Dr. William Schaffner, an infectious disease expert at Vanderbilt University:

“The findings strongly support earlier studies suggesting a role for the drug (hydroxychloroquine)”

Digging deeper…

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The study  was conducted at the Renmin Hospital of Wuhan University, in Wuhan, China.

The study design is explicitly disclosed and seems legit:

The patients were carefully chosen to exclude people with medical problems that could be made worse by hydroxychloroquine, like abnormal heart rhythms, certain eye diseases, and liver or kidney problems.

After giving informed consent, they were assigned at random to either the hydroxychloroquine or the control group. They were treated for five days, and their fevers and coughing were monitored.

They also had chest CT scans the day before the study treatment began, and the day after it ended.

Scientists hypothesize that hydroxychloroquine might work in  two possible ways:

In laboratory studies, it can stop the virus from invading cells.

And, hydroxychloroquine can also dial back an overactive immune system, which is why it can treat autoimmune diseases.

[That’s important because] a powerful immune reaction to the coronavirus is suspected of playing a role in some of the severest cases of the disease.

Skeptics are sure to point out the study’s limitations:

  • Chinese data is not to be trusted
  • It was a small sample (62 patients)
  • No patients with advanced (severe) symptoms were included
  • Patients with heart, kidney or eye issues were exclude (since known HC side effects might be exacerbated)
  • The study’s report has not been peer reviewed

The authors of the report said that the medication was promising.

But, they point out that more research is needed to clarify how HC works in treating coronavirus disease and to determine the best way to use it.

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Bottom line: The evidence is mounting, Dr. Fauci.

At some point, even you will have to concede that it’s “data” and not just anecdotes.

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Follow on Twitter @KenHoma

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One Response to “Hey, Dr. Fauci: Here’s a randomized control study for you…”

  1. Dr. Fauci gets grilled on Hydroxychloroquine… | The Homa Files Says:

    […] Hey, Dr. Fauci: Here’s a randomized control study for you… […]

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